Monday, December 28, 2009

A Viral Story

This break, I am looking at Yale medical labs that look interesting in the hopes of find a lab to do research at this summer. I am especially interested in a particular lab that focuses on how retroviruses, the family of virus that includes HIV, infect cells. While I was starting to read through some of the research papers that this lab has published, despite the papers being no Harry Potters and requiring more google searches (to understand certain terms) than a final exam (which needs google searches for procrastination's sake), they had an undeniable narrative. Badass, secretive retroviruses infilitrate immune cells and take over the cell's machinery. While this of course, is a well known tale, it gets more interesting as the lab begins to provide additional narrative detail. See cells that are attacked by retroviruses aren't as much military bases like Fort Sumter, which if captured simply provide ammunition and weapons for the virsues's machinations. No, immune cells are like naval ships, a la pirates of the carribean. If retroviruses can seize control of immune cells the lab has shown, it can steer and extend membrane connections, similar to rope ladders, to connect to a nearby immune-cell/ship, and 10 times more efficiently infilitrate and take over that cell/ship that it is in contact with. If the Cold War was America vs. Retroviruses, not only would we have been fighting a naval battle as aforementioned, but containment would have been an essentially pragmatic and necessary paradigm. The battle strategy would necessarily have included cutting down the rope bridges between ships a.k.a. inhibiting the formation of membrane connections that facilitate transfer of HIV virus (which the lab has shown can be done). These fairly choppy, incoherent analogies are just from a brief skimming of two papers, but I can't wait to uncover additional narration (hopefully I can even spend all summer unraveling the story if there is an opening in this lab that would allow me to work in it).

I got to be honest, though, maybe this post is at some level inspired by my unceasing desire to be like Barack Obama. To see how Obama might see the world with a narrative-frame-of mind, read this really inetersting article http://www.gq.com/news-politics/politics/200911/barack-obama-writing-books-writer-robert-draper?printable=true (I found this article on an awesome blog called givemesomethingtoread.com, a blog which I found out about from Sean--thanks Sean!)

1 comment:

  1. Hi dk! Just wanted to say I LOVE your blog! I admire you a lot! Please keep on writing amazing articles. I can't seem to get enough of you!

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